Functional Reconstruction of NLRs in HEK293 Cells.
نویسندگان
چکیده
Inflammasomes are molecular complexes that initiate innate immune response. They are mainly expressed by immune cells; however, molecular manipulations in these cells remain very difficult. Here, we describe a simple protocol to overexpress and activate functional NRLP3 inflammasomes in HEK293 cells.
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ورودعنوان ژورنال:
- Methods in molecular biology
دوره 1417 شماره
صفحات -
تاریخ انتشار 2016